論文

(6)発生・分化・幹細胞関連 (development・differentiation・stem cell)

LIM homeobox 2 promotes interaction between human iPS-derived hepatic progenitors and iPS-derived hepatic stellate-like cells.
Miyoshi M, Kakinuma S, Kamiya A, Tsunoda T, Tsuchiya J, Sato A, Kaneko S, Nitta S, Kawai-Kitahata F, Murakawa M, Itsui Y, Nakagawa M, Azuma S, Nakauchi H5, Asahina Y, Watanabe M.
Sci Rep. 2019 Feb 14;9(1):2072. doi: 10.1038/s41598-018-37430-9
https://www.ncbi.nlm.nih.gov/pubmed/30765795

Epigenetic silencing of Lgr5 induces senescence of intestinal epithelial organoids during the process of aging.
Uchida R, Saito Y, Nogami K, Kajiyama Y, Suzuki Y, Kawase Y, Nakaoka T, Muramatsu T, Kimura M, Saito H.
NPJ Aging Mech Dis. 2018 Dec 1;5:1.
https://www.ncbi.nlm.nih.gov/pubmed/30534415

ISGF3 with reduced phosphorylation is associated with constitutive expression of interferon-induced genes in aging cells.
Yamagami M, Otsuka M, Kishikawa T, Sekiba K, Seimiya T, Tanaka E, Suzuki T, Ishibashi R, Ohno M, Koike K.
NPJ Aging Mech Dis. 2018 Nov 15;4:11
https://www.ncbi.nlm.nih.gov/pubmed/30455980

Single-Construct Polycistronic Doxycycline-Inducible Vectors Improve Direct Cardiac Reprogramming and Can Be Used to Identify the Critical Timing of Transgene Expression.
Umei TC, Yamakawa H, Muraoka N, Sadahiro T, Isomi M, Haginiwa S, Kojima H, Kurotsu S, Tamura F, Osakabe R10, Tani H, Nara K, Miyoshi H, Fukuda K, Ieda M.
Int J Mol Sci. 2017 Aug 19;18(8)
https://www.ncbi.nlm.nih.gov/pubmed/28825623

VCAM1 acts in parallel with CD69 and is required for the initiation of oligodendrocyte myelination.
Miyamoto Y, Torii T, Tanoue A, Yamauchi J.
Nat Commun. 2016 Nov 23;7:13478.
https://www.ncbi.nlm.nih.gov/pubmed/27876794

MicroRNA Profiles Qualify Phenotypic Features of Cultured Human Corneal Endothelial Cells.
Ueno M, Asada K, Toda M, Hiraga A, Montoya M, Sotozono C, Kinoshita S, Hamuro J.
Invest Ophthalmol Vis Sci. 2016 Oct 1;57(13):5509-5517.
https://www.ncbi.nlm.nih.gov/pubmed/27768788

Gene Signature-Based Development of ELISA Assays for Reproducible Qualification of Cultured Human Corneal Endothelial Cells.
Ueno M, Asada K, Toda M, Schlotzer-Schrehardt U, Nagata K, Montoya M, Sotozono C, Kinoshita S, Hamuro J.
Invest Ophthalmol Vis Sci. 2016 Aug 1;57(10):4295-305.
https://www.ncbi.nlm.nih.gov/pubmed/27552407

Early osteoinductive human bone marrow mesenchymal stromal/stem cells support an enhanced hematopoietic cell expansion with altered chemotaxis- and adhesion-related gene expression profiles.
Sugino N, Miura Y, Yao H, Iwasa M, Fujishiro A, Fujii S, Hirai H, Takaori-Kondo A, Ichinohe T, Maekawa T.
Biochem Biophys Res Commun. 2016 Jan 22;469(4):823-9
http://www.ncbi.nlm.nih.gov/pubmed/26707642

Fibroblast Growth Factors and Vascular Endothelial Growth Factor Promote Cardiac Reprogramming under Defined Conditions.
Yamakawa H, Muraoka N, Miyamoto K, Sadahiro T, Isomi M, Haginiwa S, Kojima H, Umei T, Akiyama M, Kuishi Y, Kurokawa J, Furukawa T, Fukuda K, Ieda M.
Stem Cell Reports. 2015 Dec 8;5(6):1128-42.
http://www.ncbi.nlm.nih.gov/pubmed/26626177

ETS-related transcription factors ETV4 and ETV5 are involved in proliferation and induction of differentiation-associated genes in embryonic stem (ES) cells.
Akagi T, Kuure S, Uranishi K, Koide H, Costantini F, Yokota T.
J Biol Chem. 2015 Sep 11;290(37):22460-73.
http://www.ncbi.nlm.nih.gov/pubmed/26224636

Expression of coxsackievirus and adenovirus receptor separates hematopoietic and cardiac progenitor cells in fetal liver kinase 1-expressing mesoderm.
Tashiro K, Hirata N, Okada A, Yamaguchi T, Takayama K, Mizuguchi H, Kawabata K.
Stem Cells Transl Med. 2015 May;4(5):424-36.
http://www.ncbi.nlm.nih.gov/pubmed/25762001

miR-487b, miR-3963 and miR-6412 delay myogenic differentiation in mouse myoblast-derived C2C12 cells.
Katase N, Terada K, Suzuki T, Nishimatsu S, Nohno T.
BMC Cell Biol. 2015 Apr 30;16:13.
http://www.ncbi.nlm.nih.gov/pubmed/25925429

Down syndrome-associated haematopoiesis abnormalities created by chromosome transfer and genome editing technologies.
Kazuki Y, Yakura Y, Abe S, Osaki M, Kajitani N, Kazuki K, Takehara S, Honma K, Suemori H, Yamazaki S, Sakuma T, Toki T, Shimizu R, Nakauchi H, Yamamoto T, Oshimura M.
Sci Rep. 2014 Aug 27;4:6136.
http://www.ncbi.nlm.nih.gov/pubmed/25159877

MiR-133 promotes cardiac reprogramming by directly repressing Snai1 and silencing fibroblast signatures.
Muraoka N, Yamakawa H, Miyamoto K, Sadahiro T, Umei T, Isomi M, Nakashima H, Akiyama M, Wada R, Inagawa K, Nishiyama T, Kaneda R, Fukuda T, Takeda S, Tohyama S, Hashimoto H, Kawamura Y, Goshima N, Aeba R, Yamagishi H, Fukuda K, Ieda M.
EMBO J. 2014 Jul 17;33(14):1565-81.
http://www.ncbi.nlm.nih.gov/pubmed/24920580

3-Deazaneplanocin A (DZNep), an inhibitor of S-adenosylmethionine-dependent methyltransferase, promotes erythroid differentiation.
Fujiwara T, Saitoh H, Inoue A, Kobayashi M, Okitsu Y, Katsuoka Y, Fukuhara N, Onishi Y, Ishizawa K, Ichinohasama R, Harigae H.
J Biol Chem. 2014 Mar 21;289(12):8121-34.
http://www.ncbi.nlm.nih.gov/pubmed/24492606

Parathyroid hormone enhances hematopoietic expansion via upregulation of cadherin-11 in bone marrow mesenchymal stromal cells.
Yao H, Miura Y, Yoshioka S, Miura M, Hayashi Y, Tamura A, Iwasa M, Sato A, Hishita T, Higashi Y, Kaneko H, Ashihara E, Ichinohe T, Hirai H, Maekawa T.
Stem Cells. 2014 Mar 19.
http://www.ncbi.nlm.nih.gov/pubmed/24648356

Hsa-miR-520d induces hepatoma cells to form normal liver tissues via a stemness-mediated process.
Tsuno S, Wang X, Shomori K, Hasegawa J, Miura N.
Sci Rep. 2014 Jan 24;4:3852.
http://www.ncbi.nlm.nih.gov/pubmed/24458129

Molecular and cellular features of murine craniofacial and trunk neural crest cells as stem cell-like cells.
Hagiwara K, Obayashi T, Sakayori N, Yamanishi E, Hayashi R, Osumi N, Nakazawa T, Nishida K.
PLoS One. 2014 Jan 20;9(1):e84072.
http://www.ncbi.nlm.nih.gov/pubmed/24465393

Molecular functions of the LIM-homeobox transcription factor Lhx2 in hematopoietic progenitor cells derived from mouse embryonic stem cells.
Kitajima K, Kawaguchi M, Iacovino M, Kyba M, Hara T.
Stem Cells. 2013 Dec;31(12):2680-9.
http://www.ncbi.nlm.nih.gov/pubmed/23922318

In vivo leukemogenic potential of an interleukin 7 receptor α chain mutant in hematopoietic stem and progenitor cells.
Yokoyama K, Yokoyama N, Izawa K, Kotani A, Harashima A, Hozumi K, Tojo A.
Blood. 2013 Dec 19;122(26):4259-63.
http://www.ncbi.nlm.nih.gov/pubmed/24174626

Common developmental pathway for primitive erythrocytes and multipotent hematopoietic progenitors in early mouse development.
Yamane T, Washino A, Yamazaki H.
Stem Cell Reports. 2013 Nov 27;1(6):590-603.
http://www.ncbi.nlm.nih.gov/pubmed/24371812

Osteogenic differentiation capacity of human skeletal muscle-derived progenitor cells.
Oishi T, Uezumi A, Kanaji A, Yamamoto N, Yamaguchi A, Yamada H, Tsuchida K.
PLoS One. 2013;8(2):e56641.
http://www.ncbi.nlm.nih.gov/pubmed/23457598

Induction of human cardiomyocyte-like cells from fibroblasts by defined factors.
Wada R, Muraoka N, Inagawa K, Yamakawa H, Miyamoto K, Sadahiro T, Umei T, Kaneda R, Suzuki T, Kamiya K, Tohyama S, Yuasa S, Kokaji K, Aeba R, Yozu R, Yamagishi H, Kitamura T, Fukuda K, Ieda M.
Proc Natl Acad Sci U S A. 2013 Jul 30;110(31):12667-72.
http://www.ncbi.nlm.nih.gov/pubmed/23861494M

p63 attenuates epithelial to mesenchymal potential in an experimental prostate cell model.
Olsen JR, Oyan AM, Rostad K, Hellem MR, Liu J, Li L, Micklem DR, Haugen H, Lorens JB, Rotter V, Ke XS, Lin B, Kalland KH.
PLoS One. 2013 May 1;8(5):e62547.
http://www.ncbi.nlm.nih.gov/pubmed/23658742

Unraveling the global microRNAome responses to ionizing radiation in human embryonic stem cells.
Sokolov MV, Panyutin IV, Neumann RD.
PLoS One. 2012;7(2):e31028.
http://www.ncbi.nlm.nih.gov/pubmed/22347422

Tracing the conversion process from primordial germ cells to pluripotent stem cells in mice.
Nagamatsu G, Kosaka T, Saito S, Takubo K, Akiyama H, Sudo T, Horimoto K, Oya M, Suda T.
Biol Reprod. 2012 Jun 14;86(6):182.
http://www.ncbi.nlm.nih.gov/pubmed/22423052

Fibrosis and adipogenesis originate from a common mesenchymal progenitor in skeletal muscle.
Uezumi A, Ito T, Morikawa D, Shimizu N, Yoneda T, Segawa M, Yamaguchi M, Ogawa R, Matev MM, Miyagoe-Suzuki Y, Takeda S, Tsujikawa K, Tsuchida K, Yamamoto H, Fukada S.
J Cell Sci. 2011 Nov 1;124(Pt 21):3654-64.
http://www.ncbi.nlm.nih.gov/pubmed/22045730

CD133+ cancer stem cell-like cells derived from uterine carcinosarcoma (malignant mixed Mullerian tumor).
Choijamts B, Jimi S, Kondo T, Naganuma Y, Matsumoto T, Kuroki M, Iwasaki H, Emoto M.
Stem Cells. 2011 Oct;29(10):1485-95.
http://www.ncbi.nlm.nih.gov/pubmed/21919130

A homozygous mutant embryonic stem cell bank applicable for phenotype-driven genetic screening.
Horie K, Kokubu C, Yoshida J, Akagi K, Isotani A, Oshitani A, Yusa K, Ikeda R, Huang Y, Bradley A, Takeda J.
Nat Methods. 2011 Oct 23;8(12):1071-7.
http://www.ncbi.nlm.nih.gov/pubmed/22020066

Cell line-dependent differentiation of induced pluripotent stem cells into cardiomyocytes in mice.
Kaichi S, Hasegawa K, Takaya T, Yokoo N, Mima T, Kawamura T, Morimoto T, Ono K, Baba S, Doi H, Yamanaka S, Nakahata T, Heike T.
Cardiovasc Res. 2010 Nov 1;88(2):314-23
http://www.ncbi.nlm.nih.gov/pubmed/20547733

A Notch ligand, Delta-like 1 functions as an adhesion molecule for mast cells.
Murata A, Okuyama K, Sakano S, Kajiki M, Hirata T, Yagita H, Zuniga-Pflucker JC, Miyake K, Akashi-Takamura S, Moriwaki S, Niida S, Yoshino M, Hayashi S.
J Immunol. 2010 Oct 1;185(7):3905-12.
http://www.ncbi.nlm.nih.gov/pubmed/20810995

Metastable primordial germ cell-like state induced from mouse embryonic stem cells by Akt activation.
Yamano N, Kimura T, Watanabe-Kushima S, Shinohara T, Nakano T.
Biochem Biophys Res Commun. 2010 Feb 12;392(3):311-6.
http://www.ncbi.nlm.nih.gov/pubmed/20059970

Regulation of endoplasmic reticulum stress response by a BBF2H7-mediated Sec23a pathway is essential for chondrogenesis.
Saito A, Hino S, Murakami T, Kanemoto S, Kondo S, Saitoh M, Nishimura R, Yoneda T, Furuichi T, Ikegawa S, Ikawa M, Okabe M, Imaizumi K.
Nat Cell Biol. 2009 Oct;11(10):1197-204.
http://www.ncbi.nlm.nih.gov/pubmed/19767744

3D spheroid culture system on micropatterned substrates for improved differentiation efficiency of multipotent mesenchymal stem cells.
Wang W, Itaka K, Ohba S, Nishiyama N, Chung UI, Yamasaki Y, Kataoka K.
Biomaterials. 2009 May;30(14):2705-15.
http://www.ncbi.nlm.nih.gov/pubmed/19215979