論文

(1)血漿・血清を使用したmiRNA解析

A serum microRNA classifier for the diagnosis of sarcomas of various histological subtypes.
Asano N, Matsuzaki J, Ichikawa M, Kawauchi J, Takizawa S, Aoki Y, Sakamoto H, Yoshida A, Kobayashi E, Tanzawa Y, Nakayama R, Morioka H, Matsumoto M, Nakamura M, Kondo T, Kato K, Tsuchiya N, Kawai A, Ochiya T
Nat Commun. 2019 Mar 21;10(1):1299. doi: 10.1038/s41467-019-09143-8
https://www.ncbi.nlm.nih.gov/pubmed/?term=A+serum+microRNA+classifier+for+the+diagnosis+of

Serum microRNAs and chronic periodontitis: A case-control study.
Yoneda T, Tomofuji T, Ekuni D, Azuma T, Maruyama T, Fujimori K, Sugiura Y, Morita M.
Arch Oral Biol. 2019 Mar 13;101:57-63. doi: 10.1016/j.archoralbio.2019.03.009.
https://www.ncbi.nlm.nih.gov/pubmed/30889506

Characterization of a novel microRNA, miR-188, elevated in serum of muscular dystrophy dog model.
Shibasaki H, Imamura M, Arima S, Tanihata J, Kuraoka M, Matsuzaka Y, Uchiumi F, Tanuma S, Takeda S.
PLoS One. 2019 Jan 30;14(1):e0211597. doi: 10.1371/journal.pone.0211597. eCollection 2019.
https://www.ncbi.nlm.nih.gov/pubmed/30699200

Risk prediction models for dementia constructed by supervised principal
component analysis using miRNA expression data.
Shigemizu D, Akiyama S, Asanomi Y, Boroevich KA, Sharma A, Tsunoda T, Matsukuma K, Ichikawa M, Sudo H, Takizawa S, Sakurai T, Ozaki K, Ochiya T, Niida S.
Commun Biol. 2019 Feb 25;2:77. doi: 10.1038/s42003-019-0324-7. eCollection 2019.
https://www.ncbi.nlm.nih.gov/pubmed/30820472

Large-scale circulating microRNA profiling for the liquid biopsy of prostate cancer.
Urabe F, Matsuzaki J, Yamamoto Y Kimura T, Hara T, Ichikawa M, Takizawa S, Aoki Y, Niida S, Sakamoto H, Kato K, Egawa S, Fujimoto H, Ochiya T.
Clin Cancer Res. 2019 Feb 26. pii: clincanres.2849.2018. doi: 10.1158/1078-0432.CCR-18-2849.
https://www.ncbi.nlm.nih.gov/pubmed/30808771

Circulating miRNA Panels for Specific and Early Detection in Bladder Cancer.
Usuba W, Urabe F, Yamamoto Y, Matsuzaki J, Sasaki H, Ichikawa M, Takizawa S, Aoki Y, Niida S, Kato K, Egawa S, Chikaraishi T, Fujimoto H, Ochiya T.
Cancer Sci. 2018 Nov 1.
https://www.ncbi.nlm.nih.gov/pubmed/30382619

Integrated extracellular microRNA profiling for ovarian cancer screening.
Yokoi A, Matsuzaki J, Yamamoto Y, Yoneoka Y, Takahashi K, Shimizu H, Uehara T, Ishikawa M, Ikeda S, Sonoda T, Kawauchi J, Takizawa S, Aoki Y, Niida S, Sakamoto H, Kato K, Kato T, Ochiya T.
Nat Commun. 2018 Oct 17;9(1):4319. doi: 10.1038/s41467-018-06434-4.
https://www.ncbi.nlm.nih.gov/pubmed/30333487

Circulating microRNAs as potential biomarkers to detect transformation of Barrett's oesophagus to oesophageal adenocarcinoma.
Matsuzaki J1, Suzuki H.
BMJ Open Gastroenterol. 2017 Sep 8;4(1):e000160.
https://www.ncbi.nlm.nih.gov/pubmed/29177063

Depleted tumor suppressor miR-107 in plasma relates to tumor progression and is a novel therapeutic target in pancreatic cancer.
Imamura T, Komatsu S, Ichikawa D, Miyamae M, Okajima W, Ohashi T, Kiuchi J, Nishibeppu K, Konishi H, Shiozaki A, Morimura R, Ikoma H, Ochiai T, Okamoto K, Taniguchi H, Otsuji E.
Sci Rep. 2017 Jul 18;7(1):5708
https://www.ncbi.nlm.nih.gov/pubmed/28720759

MicroRNA Profiles Qualify Phenotypic Features of Cultured Human Corneal Endothelial Cells.
Ueno M, Asada K, Toda M, Hiraga A, Montoya M, Sotozono C, Kinoshita S, Hamuro J.
Invest Ophthalmol Vis Sci. 2016 Oct 1;57(13):5509-5517.
https://www.ncbi.nlm.nih.gov/pubmed/27768788

Circulating miR-223 in Oral Cancer: Its Potential as a Novel Diagnostic Biomarker and Therapeutic Target.
Tachibana H, Sho R, Takeda Y, Zhang X, Yoshida Y, Narimatsu H, Otani K, Ishikawa S, Fukao A, Asao H, Iino M.
PLoS One. 2016 Jul 21;11(7):e0159693.
https://www.ncbi.nlm.nih.gov/pubmed/27441818

Extracellular vesicle miR-7977 is involved in hematopoietic dysfunction of mesenchymal stromal cells via poly(rC) binding protein 1 reduction in myeloid neoplasms.
Horiguchi H, Kobune M, Kikuchi S, Yoshida M, Murata M, Murase K, Iyama S, Takada K, Sato T, Ono K, Hashimoto A, Tatekoshi A, Kamihara Y, Kawano Y, Miyanishi K, Sawada N, Kato J.
Haematologica. 2016 Apr;101(4):437-47
http://www.ncbi.nlm.nih.gov/pubmed/26802051

Novel combination of serum microRNA for detecting breast cancer in the early stage.
Shimomura A, Shiino S, Kawauchi J, Takizawa S, Sakamoto H, Matsuzaki J, Ono M, Takeshita F, Niida S, Shimizu C, Fujiwara Y, Kinoshita T, Tamura K, Ochiya T.
Cancer Sci. 2016 Mar;107(3):326-34.
http://www.ncbi.nlm.nih.gov/pubmed/26749252

Microarray Technology and Its Applications for Detecting Plasma microRNA Biomarkers in Digestive Tract Cancers.
Konishi H, Ichikawa D, Arita T, Otsuji E.
Methods Mol Biol. 2016;1368:99-109.
http://www.ncbi.nlm.nih.gov/pubmed/26614071

Circulating microRNA Profiles in Patients with Type-1 Autoimmune Hepatitis.
Migita K, Komori A, Kozuru H, Jiuchi Y, Nakamura M, Yasunami M, Furukawa H, Abiru S, Yamasaki K, Nagaoka S, Hashimoto S, Bekki S, Kamitsukasa H, Nakamura Y, Ohta H, Shimada M, Takahashi H, Mita E, Hijioka T, Yamashita H, Kouno H, Nakamuta M, Ario K, Muro T, Sakai H, Sugi K, Nishimura H, Yoshizawa K, Sato T, Naganuma A, Komatsu T, Oohara Y, Makita F, Tomizawa M, Yatsuhashi H.
PLoS One. 2015 Nov 17;10(11):e0136908.
https://www.ncbi.nlm.nih.gov/pubmed/26575387

Plasma microRNA profiles: identification of miR-744 as a novel diagnostic and prognostic biomarker in pancreatic cancer.
Miyamae M, Komatsu S, Ichikawa D, Kawaguchi T, Hirajima S, Okajima W, Ohashi T, Imamura T, Konishi H, Shiozaki A, Morimura R, Ikoma H, Ochiai T, Okamoto K, Taniguchi H, Otsuji E.
Br J Cancer. 2015 Nov 17;113(10):1467-76.
http://www.ncbi.nlm.nih.gov/pubmed/26505678

Differences in serum microRNA profiles in hepatitis B and C virus infection.
Akamatsu S, Hayes CN, Tsuge M, Miki D, Akiyama R, Abe H, Ochi H, Hiraga N, Imamura M, Takahashi S, Aikata H, Kawaoka T, Kawakami Y, Ohishi W, Chayama K.
J Infect. 2015 Mar;70(3):273-87.
http://www.ncbi.nlm.nih.gov/pubmed/25452043

MicroRNA markers for the diagnosis of pancreatic and biliary-tract cancers.
Kojima M, Sudo H, Kawauchi J, Takizawa S, Kondou S, Nobumasa H, Ochiai A.
PLoS One. 2015 Feb 23;10(2):e0118220.
http://www.ncbi.nlm.nih.gov/pubmed/25706130

Plasma microRNA profiles: identification of miR-25 as a novel diagnostic and monitoring biomarker in oesophageal squamous cell carcinoma.
Komatsu S, Ichikawa D, Hirajima S, Kawaguchi T, Miyamae M, Okajima W, Ohashi T, Arita T, Konishi H, Shiozaki A, Fujiwara H, Okamoto K, Yagi N, Otsuji E.
Br J Cancer. 2014 Oct 14;111(8):1614-24.
http://www.ncbi.nlm.nih.gov/pubmed/25117812

Profiles of Extracellular miRNAs in the Aqueous Humor of Glaucoma Patients Assessed with a Microarray System.
Tanaka Y, Tsuda S, Kunikata H, Sato J, Kokubun T, Yasuda M, Nishiguchi KM, Inada T, Nakazawa T.
Sci Rep. 2014 May 28;4:5089.
http://www.ncbi.nlm.nih.gov/pubmed/24867291

Circulating microRNAs in autoimmune thyroid diseases.
Yamada H, Itoh M, Hiratsuka I, Hashimoto S.
Clin Endocrinol (Oxf). 2014 Feb 17.
http://www.ncbi.nlm.nih.gov/pubmed/24533739

Hepatitis B virus-specific miRNAs and Argonaute2 play a role in the viral life cycle.
Hayes CN, Akamatsu S, Tsuge M, Miki D, Akiyama R, Abe H, Ochi H, Hiraga N, Imamura M, Takahashi S, Aikata H, Kawaoka T, Kawakami Y, Ohishi W, Chayama K.
PLoS One. 2012;7(10):e47490.
http://www.ncbi.nlm.nih.gov/pubmed/23091627

Circulating microRNAs involved in multiple sclerosis.
Siegel SR, Mackenzie J, Chaplin G, Jablonski NG, Griffiths L.
Mol Biol Rep. 2012 May;39(5):6219-25. 
http://www.ncbi.nlm.nih.gov/pubmed/22231906

Detection of gastric cancer-associated microRNAs on microRNA microarray comparing pre- and post-operative plasma.
Konishi H, Ichikawa D, Komatsu S, Shiozaki A, Tsujiura M, Takeshita H, Morimura R, Nagata H, Arita T, Kawaguchi T, Hirashima S, Fujiwara H, Okamoto K, Otsuji E.
Br J Cancer. 2012 Feb 14;106(4):740-7. 
http://www.ncbi.nlm.nih.gov/pubmed/22262318