Features of 3D-Gene®
Until now, a flat glass DNA microarray substrate had been sought for the stabilization of spot morphology. However, by developing a DNA microarray substrate utilizing “black resin substrate with uneven structures,” which breaks through the common use of “flat glass substrate,” Toray succeeded in increasing gene detection sensitivity by about 100-fold. Four features of 3D-Gene® are presented below.
4 Features
Black resin substrate
Black resin substrate substantially decreases background noise and enables the detection of low expression genes that were previously hidden in noise.
Fine columnar structure
The adoption of uneven columnar structure for the detection area of substrate enables the stabilization of spot morphology and the acquisition of a uniform detected image.
Special surface modification for probe immobilization
Toray's unique surface treatment technology enables dense and uniform immobilization of probes on the substrate surface to improve detection capability.
Bead agitation
By agitating solution on the substrate using microbeads, solution spreads evenly, and reactivity (signal intensity) of detected genes dramatically increases.
Highly sensitive detection contributes to the progression of gene analysis
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